Marianne Elizabeth Houghton

F, #118591, b. 18 February 1957, d. 9 November 2015

Family 1: Jerry Loebach

  • Marriage*: Marianne Elizabeth Houghton married Jerry Loebach.1
  • Divorce*: Marianne Elizabeth Houghton and Jerry Loebach were divorced.

Family 2: (?) King

  • Marriage*: Marianne Elizabeth Houghton married (?) King.

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthFeb 18, 1957Manistique, MI, USA
Marriage1
Divorce
Marriage
DeathNov 9, 2015Saint Ignace, MI, USA
Pedigree

Citations

  1. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Wanda Mae Houghton

F, #118592, b. circa 1943

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1943MI, USA
Pedigree

Ashly Sharae Houghton

F, #118593, b. circa 1987

Family: Dr. Kyle Fink PhD

Biography

A Contributor to Houghton Surname ProjectY
Corresponded with authorN
Birthcirca 1987MI, USA
Marriage1
Contributn
Living2022West Sacramento, CA, USA
CorrespondJul, 2022Ashly Fink
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Bradley James Houghton1

M, #118594, b. circa 1985, d. January 2022

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birthcirca 1985MI, USA
ResidenceSault Sainte Marie, MI, USA
DeathJan, 2022MI, USA1
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.

Jordan Jackson Houghton1

M, #118595, b. circa 1997

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birthcirca 1997MI, USA2
Living2022Sault Sainte Marie, MI, USA
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Michael Joseph Houghton1

M, #118596, b. January 1961

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
BirthJan, 1961MI, USA2
Living2022Engadine, MI, USA
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Kim Houghton1

M, #118597

Family: Kathy (?)

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthMI, USA
No Childrn
Marriage
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.

Patty Houghton1

F, #118598

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
BirthMI, USA2
Living2022Sault Ste Marie, MI, USA3
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.
  3. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Kayla Houghton1

F, #118599

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Garrett Houghton1

M, #118600

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Jeremy Loebach1

M, #118601

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Bridgette Loebach1

F, #118602

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Blake Loebach1

M, #118603

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Jacob Loebach1

M, #118604

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Joey King1

M, #118605

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Stephen Houghton1

M, #118606, b. circa 1988

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1988WA, USA1
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Daryl David Houghton Jr1

M, #118607, b. circa 1996

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1996WA, USA1
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Maria Houghton1

F, #118608, b. circa 1999

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1999WA, USA1
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Michael Vern Houghton1

M, #118609, b. circa 1988

Family: Samantha (?)

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birthcirca 1988MI, USA2
Marriage3
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.
  3. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

April Rose Houghton1

F, #118610, b. circa 1986

Family: Kris Masters

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birthcirca 1986MI, USA2
Children+Together they had 3 children and have adopted 6 children. They now (2022) have a total of 9.
Trevin Masters (age 16)
Teegen Masters (age 13)
Karsin Masters (age 9)
Gavin Masters (age 9)
Parker Masters (age 9)
Danika Masters (age 7)
Zaity Masters (aqe 6)
Za'Rae Masters (age 6)
Kristopher Masters Jr. (age 1)3
Marriage3
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.
  3. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Andrew Jacob Houghton1

M, #118611, b. circa 1992

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1992MI, USA2
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Dr. Kyle Fink PhD1

M, #118612, d. January 1984

Family: Ashly Sharae Houghton

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
DeathJan, 1984
Education2008University of California, Davis, Medical Center, Stem Cell Program
Sacramento, California
Ruth L. Kirchstein NRSA Postdoctoral Scholar, Institute for Regenerative Cures, Stem Cell Program, 2016

University of Nantes
Nantes, France
Ph.D., Neuroscience, INSERM UMR643, 2013

Central Michigan University
Mount Pleasant, Michigan
Ph.D., Neuroscience, Field Neurosciences Institute of Restorative Neurology, 2013

Central Michigan University
Mount Pleasant, Michigan
M.S., Experimental Psychology, 2010

University of Portland
Portland, Oregon
B.A., Psychology with Neuroscience Focus, The BRAIN Lab, 2008
Marriage2
OccupationUC Davis, Davis, CA, USA, Assistant Professor
Neurology and Institute for Regenerative Cures
Living2022West Sacramento, CA, USA
Note2022UC Davis, Website: Research Interests

Dr. Fink received his Ph.D. in Neuroscience from Central Michigan University and the University of Nantes. He has focused on therapeutic development for neurodegenerative diseases, brain injury, and some forms of brain cancer. His research team focuses on genetically-linked neurological disorders such as CDKL5 deficiency (rare intractable pediatric epilepsy), Angelman’s Syndrome, and Huntington’s disease that are targetable with gene editing molecules in addition to some forms of brain cancer. His lab is identifying candidate sequences through whole genome sequencing and transcriptomics using a bioinformatics approach for structural variation discovery and genotyping that identify underlying common genetic variants. Gene variants linked to disease phenotype are examined for “actionable domains” for which we create therapeutic artificial transcription factors. Patient-derived samples can be used to create in vitro neuronal disease-in-a-dish models using novel induced neuron techniques. His team builds on the existing strengths and expertise at UC Davis and utilizes the necessary resources to develop a therapeutic pipeline in which precision medicine can be used to identify novel disease causing genetic variants to advance Precision Neurotherapeutics to clinical applications.

His current research focuses on two major goals 1) The therapeutic application of transcription activator-like effector (TALE) and clustered regularly interspaced short palindrome repeats (CRISPR) to modify gene expression in genetically-linked pediatric neurological diseases; and 2) the development of delivery systems that can safely and efficaciously target the central nervous system with our novel gene editing platforms. These goals specifically address: A) how to deliver these potent therapeutics to maximize the biodistribution in the central nervous system; B) how to increase the specificity of each construct to limiting off-target effects; and C) how to minimize the immune response to increase safety and the therapeutic potential of this approach. They have used known information regarding JHD and CDKL5 deficiency to guide construction of potent, precise gene modifying modalities- CRISPR/Cas9 and TALE. These platforms can turn on or enhance transcription of a gene, transcriptionally silence expression, cause permanent epigenetic changes, or remove a piece of DNA via targeted double stranded breaks essentially allowing for custom modifications to be made at the genomic level.
Pedigree

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Sharon Ranay1

F, #118613, b. circa 1964

Family: William Vern Houghton

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birthcirca 1964
Marriage
Pedigree

Citations

  1. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Adriana C. Strunk

F, #118614, b. 13 December 1951

Family: Stanley Ray Houghton

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
BirthDec 13, 1951
Marriage
Pedigree

Carmen Anita Houghton

F, #118615, b. 19 February 1974

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthFeb 19, 1974
Pedigree

Bridgette C. Houghton

F, #118616, b. 22 February 1976

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthFeb 22, 1976
Pedigree

Cheryl Lynn Houghton

F, #118617, b. 17 November 1971

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthNov 17, 1971
Pedigree

Darrill Lee Houghton

M, #118618, b. 1 February 1946, d. 9 October 1955

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
BirthFeb 1, 1946
DeathOct 9, 1955
Pedigree

Michelle Elaine Houghton

F, #118619, b. 1970

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth1970
Pedigree

Beatrice Velma Houghton

F, #118620, b. 1921, d. 1962

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birth1921
Death1962
Pedigree